Protamine Insulin and Zinc Protamine Insulin

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Further Observations on Protamine Zinc Insulin in Clinical Diabetes

One of the main difficulties that the average practitioner encounters regarding the use of msulin in clinical diabetes is the adjustment the proper dosage, on account of insulin having no fixed or standard dosage of its own. The result is that, if proper dosages are not employed, there is either little or no reduction in the blood-sugar level if the dose \s too small, or there is dangerous osci...

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Protamine zinc insulin combined with sodium selenite improves glycometabolism in the diabetic KKAy mice

Long-term, high dosage protamine zinc insulin (PZI) treatments produce adverse reactions. The trace element selenium (Se) is a candidate for the prevention of diabetes due to anti-oxidative stress activity and the regulation of glycometabolism. In this study, we aimed to investigate the anti-diabetic effects of a combination of PZI and Se on type 2 diabetes. Diabetic KKAy mice were randomized i...

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ژورنال

عنوان ژورنال: BMJ

سال: 1937

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.3975.541